Back to search

Article

Capillarisenol C, a novel bisphenol from Artemisia capillaris, induces autophagic death in hepatocellular carcinoma through endoplasmic reticulum stress

2022-09-15

Abstract excerpt

In our previous work, we isolated a novel bisphenol named capillarisenol C (Cap C) from Artemisia capillaris . Preliminary studies indicated potential anti-hepatocellular carcinoma (HCC) activity. However, its mechanism remains unclear. In this study, we aimed to investigate the function and molecular mechanism of the anti-HCC activity of Cap C. First, We evaluated the inhibitory effect of Cap C on the viability o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c6aadbe6-85fa-55a0-94bd-a69fe7456596
DOI
10.21203/rs.3.rs-2043984/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Capillarisenol C, a novel bisphenol from Artemisia capillaris, induces autophagic death in hepatocellular carcinoma through endoplasmic reticulum stressDOI 10.21203/rs.3.rs-2043984/v1
Identification of bioactive and anticancer properties of Bidens pilosa L. in-vitro evidenceSemantic proximity
Gastrointestinal Cancer Therapeutics via Triggering Unfolded Protein Response and Endoplasmic Reticulum Stress by 2-ArylbenzofuranSemantic proximity
The mechanism of CPT1A involved in hepatocellular carcinoma growth and Bufalin regulates malignant behavior of hepatocellular carcinoma via CPT1ASemantic proximity
Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinomaSemantic proximity
Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosisSemantic proximity
Natural Flavonoids Quercetin and Kaempferol Targeting G2/M Cell Cycle-Related Genes and Synergize with Smac Mimetic LCL-161 to Induce Necroptosis in Cholangiocarcinoma CellsSemantic proximity
The potential mechanism and chemical compounds contributed to Psoraleae Fructus-induced hepatotoxicity from the aspect of mitochondrial dysfunctionSemantic proximity
Evaluation of the effect of biochanin b and Sorafenib on cell survival, growth, migration, colony formation and apoptosis in hepatocellular carcinomaSemantic proximity
Deciphering the effect of Potentilla fulgens root extract against healthy HUVEC cell line and cancer cell lines (A549 and SKOV-3)Semantic proximity
Ailanthone blocks mitophagy to promote mtDNA leakage through BAX-BAK1 pores and suppress hepatocellular carcinoma cell proliferationSemantic proximity
Pharmacoinformatics Analysis Reveal Flavonoids and Diterpenoids from Andrographis Paniculata and Thespesia Populnea as Potential Modulators of Hepatitis B Virus Induced Hepatocellular CarcinomaSemantic proximity
Transcriptomic Insights into the Antitumor Mechanism of Bufalin in Hepatocellular Carcinoma Cell HepG2Semantic proximity
Select a neighboring publication to make it the new centre.