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<p class="MDPI12titleori"><em style="mso-bidi-font-style: normal;"><span lang="EN-US" style="mso-bidi-font-weight: bold;">Pseudomonas aeruginosa</em><span lang="EN-US" style="mso-bidi-font-weight: bold;"> Phage Cocktails: Rational Design and Efficacy against Mouse Wound and Systemic Infection

2025-11-26

Abstract excerpt

Phages show efficacy against multidrug-resistant Pseudomonas aeruginosa, but limited host ranges require combining them in cocktails. In this work, we characterized 25 P. aeruginosa phages, developed therapeutic cocktails active against diverse clinical isolates, and tested phage efficacy in a mouse incisional wound model. These phages represent seven genera, and genomic and phenotypic analyses indicate that 24/25...

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Literature Corpus work
c5ceaa92-e4c0-558d-92c4-1888297e101e
DOI
10.20944/preprints202511.2113.v1
Open publication

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<p class="MDPI12titleori"><em style="mso-bidi-font-style: normal;"><span lang="EN-US" style="mso-bidi-font-weight: bold;">Pseudomonas aeruginosa</em><span lang="EN-US" style="mso-bidi-font-weight: bold;"> Phage Cocktails: Rational Design and Efficacy against Mouse Wound and Systemic InfectionDOI 10.20944/preprints202511.2113.v1
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