Article

Vaginal metabolome signatures of high-risk HPV infection trajectories in HIV-negative premenopausal women

2026-04-22

Abstract excerpt

Persistent detection of high-risk human papillomavirus (HPV) is required for cervical carcinogenesis, yet the metabolic phenotype associated with distinct HPV transition states remains incompletely defined. We analyzed vaginal metabolomics data from 71 HIV-negative, non-smoking, premenopausal women without other sexually transmitted infections, grouped by three-visit HPV trajectories: persistent negative (NNN, n=2...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c5559efa-1cbb-5089-a5ed-7b3068e802d7
DOI: 10.64898/2026.04.21.26351401

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Vaginal metabolome signatures of high-risk HPV infection trajectories in HIV-negative premenopausal womenDOI 10.64898/2026.04.21.26351401Read

Microbial and metabolic profiles associated with HPV infection and cervical intraepithelial neoplasia: a multi-omics studySemantic proximity Read

A Crosstalk Analysis of high-risk human papillomavirus, microbiota and vaginal metabolome in cervicovaginal microenvironmentSemantic proximity Read

HPV-associated cervicovaginal microbiome and host metabolome characteristicsSemantic proximity Read

Distinct cervical microbiome and metabolite profiles before and after menopause: implications for cervical cancer progressionSemantic proximity Read

GC–MS-based untargeted plasma metabolomics identifies a 2-biomarker panel for possible diagnosis of precancerous cervical intraepithelial neoplasia stages from cervical cancerSemantic proximity Read

Multi-omics data integration reveals metabolome as the top predictor of the cervicovaginal microenvironmentSemantic proximity Read

Co-evolution of vaginal microbiome and cervical cancer.Semantic proximity Read

Integration of multi-omics data improves prediction of cervicovaginal microenvironment in cervical cancerSemantic proximity Read

Plasma Metabolic Phenotypes of HPV-Associated versus Smoking-Associated Head and Neck Cancer and Patient Survival.Semantic proximity Read

Functional microbiome features distinguish clinical trajectories in low-grade cervical lesionsSemantic proximity Read

High-throughput metabolomics identifies new biomarkers for cervical cancerSemantic proximity Read

Characteristics of the vaginal microbiota and vaginal metabolites in women with cervical dysplasiaSemantic proximity Read