Article

Transcriptomic Analysis of Patients With Clinical Suspicion of Maturity-onset Diabetes of the Young (MODY) With a Negative Genetic Diagnosis

2021-10-11

Abstract excerpt

<title>Abstract</title> <p>BackgroundThe personalized management of each type of Mature-onset diabetes of the young (MODY), a non-autoimmune monogenic form of diabetes mellitus, achieves both avoiding invasive therapies and better defining the patient's prognosis and reducing future misdiagnoses by performing a screening family. Positive genetic diagnosis is achieved in only around 50% of patients with clinical c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c52534b5-179f-5b3b-a838-383efe1b49b8
DOI: 10.21203/rs.3.rs-944634/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptomic Analysis of Patients With Clinical Suspicion of Maturity-onset Diabetes of the Young (MODY) With a Negative Genetic DiagnosisDOI 10.21203/rs.3.rs-944634/v1Read

Transcriptomic analysis of patients with clinical suspicion of maturity-onset diabetes of the young (MODY) with a negative genetic diagnosis.Semantic proximity Read

Genetic Variants and Therapeutic Approaches in Maturity-Onset Diabetes of the Young: A Retrospective AnalysisSemantic proximity Read

Update on clinical screening of maturity-onset diabetes of the young (MODY)Semantic proximity Read

Undiagnosed MODY: Time for Action.Semantic proximity Read

Maturity Onset Diabetes of the Young (MODY) is not always monogenic: candidate genes involved in a Latino PopulationSemantic proximity Read

Study of Thirteen Causal Genes in Turkish Patients with Clinically Suspected Maturity-Onset Diabetes of the Young (MODY) using a Targeted Next-Generation Sequencing PanelSemantic proximity Read

Monogenic diabetes in adults: what are the new developments?Semantic proximity Read

MODY is prevalent in later-onset diabetes, has potential for targeted therapy but is challenging to identifySemantic proximity Read

Low genetic confirmation rate in South Indian subjects with a clinical diagnosis of maturity-onset diabetes of the young (MODY) who underwent targeted next-generation sequencing for 13 genes.Semantic proximity Read

Maturity-onset diabetes of the young: update and perspectives on diagnosis and treatmentSemantic proximity Read

Targeted sequencing identifies novel variants in common and rare MODY genesSemantic proximity Read

The Importance of Molecular Genetic Testing for Precision Diagnostics, Management, and Genetic Counseling in MODY Patients.Semantic proximity Read