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Maturity-onset diabetes of the young: update and perspectives on diagnosis and treatment

9 Jan 2020

Abstract excerpt

Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of monogenic disorders characterized by ß-cell dysfunction. MODY accounts for between 2% and 5% of all diabetes cases, and distinguishing it from type 1 or type 2 diabetes is a diagnostic challenge. Recently, MODY-causing mutations have been identified in 14 different genes. Sanger DNA sequencing is the gold standard for identifying...

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PMID: 31914718
DOI: 10.12701/yujm.2019.00409

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