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Article

Prevention of UVA-Induced Oxidative Damage in Human Dermal Fibroblasts by New UV Filters, Assessed Using a Novel In Vitro Experimental System

7 Jan 2014

Abstract excerpt

BACKGROUND: UVA rays present in sunlight are able to reach the dermal skin layer generating reactive oxygen species (ROS) responsible for oxidative damage, alterations in gene expression, DNA damage, leading to cell inflammation, photo-ageing/-carcinogenesis. Sunscreens contain UV filters as active ingredients that absorb/reflect/dissipate UV radiation: their efficiency depends on their spectral profile and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24409282
DOI: 10.1371/journal.pone.0083401

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