Expression Dynamics and Diagnostic Potential of miR‑124‑3p, miR‑485‑5p, MAPKAPK5‑AS1, and PKMYT1AR in Glioblastoma

Abstract excerpt

<title>Abstract</title> <p> <bold>Introduction</bold> : Glioblastoma (GBM) Glioblastoma, the most common primary malignant brain tumor in adults, exhibits aggressive behavior and resistance to conventional therapies, resulting in poor prognosis with median survival of approximately 15 months. Early diagnosis and identification of novel therapeutic targets are critical for improving patient outcomes. This study...

Topics

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• Bioinformatics and Genomic Networks
• Cancer, Hypoxia, and Metabolism
• Cancer-related molecular mechanisms research
• Ferroptosis and cancer prognosis
• Glioma Diagnosis and Treatment
• MicroRNA in disease regulation
• Microtubule and mitosis dynamics
• RNA Research and Splicing

Identifiers and source

Literature Corpus work

c4c91d7a-8f87-55d5-83fe-8767c10af322

DOI

10.21203/rs.3.rs-9664820/v1