Key genes altered in glioblastoma based on bioinformatics (Review)

Abstract excerpt

Glioblastoma multiforme (GBM) is an aggressive brain tumor with poor prognosis. Recent advancements in bioinformatics have contributed to uncovering the genetic alterations that underlie the development and progression of GBM. Analysis of extensive genomic data led to the identification of significant pathways involved in GBM, such as the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways, alongside key genes...

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• Bioinformatics and Genomic Networks
• Ferroptosis and cancer prognosis
• Genetics, Bioinformatics, and Biomedical Research