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Article

Increased chromosome translocations and aneuploidy in peripheral blood lymphocytes of patients having revision arthroplasty of the hip

2001-09-01

Abstract excerpt

The long-term biological effects of wear debris are unknown. We have investigated whether there is any evidence of cumulative mutagenic damage in peripheral blood lymphocytes of patients undergoing revision arthroplasty of predominantly metal-on-plastic total hip replacements compared with those at primary arthroplasty. There was a threefold increase in aneuploidy and a twofold increase in chromosomal translocatio...

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Identifiers and source

Literature Corpus work
c47adfe0-30b8-5251-bac6-07e679038602
DOI
10.1302/0301-620x.83b7.0831075
Open publication

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Increased chromosome translocations and aneuploidy in peripheral blood lymphocytes of patients having revision arthroplasty of the hipDOI 10.1302/0301-620x.83b7.0831075
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