Article

SHED-derived Exosomes Ameliorate Hyposalivation Caused by Sjögren Syndrome via Akt/GSK-3β/Slug-mediated ZO-1 Expression

2022-02-10

Abstract excerpt

<title>Abstract</title> <p><bold>Objective</bold>: To explore the therapeutic role and mechanism of exosomes obtained from the supernatant of stem cells derived from human exfoliated deciduous teeth (SHED-exos) in sialadenitis caused by Sjögren syndrome (SS).<bold>Methods: </bold>SHED-exos were administered to the submandibular glands (SMGs) of 14-week-old nonobese diabetic (NOD) mice, an animal model of the clin...

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Literature Corpus work: c41b3176-f156-5149-9062-580e3fcd2464
DOI: 10.21203/rs.3.rs-1305483/v1

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