Article

Knockdown of Son, a mouse homologue of the ZTTK syndrome gene, causes neuronal migration defects and dendritic spine abnormalities.

2020-05-20

Abstract excerpt

<title>Abstract</title> <p>Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome, a rare congenital anomaly syndrome characterized by intellectual disability, brain malformation, facial dysmorphism, musculoskeletal abnormalities, and some visceral malformations is caused by<italic> de novo</italic> heterozygous mutations of the <italic>SON</italic> gene. The nuclear protein SON is involved in gene transcription and RNA splic...

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Literature Corpus work: c3d35c6d-7cea-5ac5-bae6-b0cab3da9ce3
DOI: 10.21203/rs.3.rs-17672/v2

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