Article

The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway

2021-01-21

Abstract excerpt

<h4>Background: </h4> Hyperactivation of mechanistic target of rapamycin (mTOR) signaling pathway is involved in the regulation of cellular growth, proliferation, and more in general, is a common phenomenon in most types of cancers. Thus, natural substances targeting this pathway can be of great therapeutic potential in supporting the treatment of tumor patients. Rhus tripartita (Ucria) Grande is a plant growing i...

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Literature Corpus work: c39e6e94-a776-5cee-b60b-1a44558b0ceb
DOI: 10.21203/rs.3.rs-138978/v1

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