Article

Germinal center BCR maturation in appendicitis reveals a role for antigen-specific adaptive immune responses during disease

2024-02-04

Abstract excerpt

Appendicitis is one of the most common abdominal emergencies globally, yet little is understood about the inflammatory mechanisms or potential drivers of disease. Neutrophil inflammation and increased cytokine expression such as IL-6 and IL-8 are hallmarks of appendicitis inflammation. However, early histological studies identified increased T and B cell infiltration during appendicitis, providing support for adap...

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Literature Corpus work: c35c532c-6375-5585-83a4-7d5f2c45ddaf
DOI: 10.1101/2024.01.31.578312

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