Article

Metabolomic profiling of pancreatic adenocarcinoma reveals fundamental clinical features

2021-02-02

Abstract excerpt

In this study, we perform the metabolomics profiling of 77 PDAC patient-derived tumor xenografts (PDTX) to investigate the relationship of metabolic profiles with overall survival (OS) in PDAC patients, tumor phenotypes and resistance to five anticancer drugs (gemcitabine, oxaliplatin, docetaxel, SN-38 and 5-Fluorouracil). We identified a metabolic signature that was able to predict the clinical outcome of PDAC pa...

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Literature Corpus work: c22f1838-192e-5f0c-a2b5-7eba12a56fe9
DOI: 10.1101/2021.02.01.429087

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