Article

Antitumour effect of neoantigen-reactive T cells induced by RNA mutanome vaccine in mouse lung cancer

2021-05-25

Abstract excerpt

<title>Abstract</title> <p>Purpose Mutation-specific T-cell response to epithelial cancers and T-cell-based immunotherapy has been successfully used to treat several human solid cancers. We aimed to investigate the antitumour effect of neoantigen-reactive T(NRT) cells induced by RNA mutanome vaccine, which may serve as a feasible and effective therapeutic approach for lung cancer. Methods We predicted candidate...

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Literature Corpus work: c21332c7-355c-53ee-aa9b-235233f68f61
DOI: 10.21203/rs.3.rs-548836/v1

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