Article

Increased blood–brain barrier leakage in schizophrenia spectrum disorders compared to healthy controls in dynamic contrast-enhanced magnetic resonance imaging

2023-12-13

Abstract excerpt

<h4>Background</h4> There is growing evidence for inflammatory mechanisms in schizophrenia spectrum disorders (SSD) that have been associated with blood-brain barrier (BBB) disruption. Previous studies investigating the BBB in SSD focused on cerebrospinal fluid (CSF) markers, that cannot adequately assess BBB integrity. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) represents a sensitive method fo...

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Literature Corpus work: c192751e-22a1-50d2-b093-c6c8fcd9ae13
DOI: 10.1101/2023.12.12.23299782

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