Article

Lipoprotein(a) is associated with higher DNA damage in patients with heterozygous familial hypercholesterolemia

2023-12-28

Abstract excerpt

Heterozygous familial hypercholesterolemia (HeFH) is a frequent autosomal-dominant inherited disorder associated with premature cardiovascular disease (CVD). HeFH subjects have a higher lipoprotein(a) (Lp(a)) concentration than the general population. Patients with FH are exposed to elevated levels of LDL from birth and ox-LDL may induce other oxidation pathways. The aim of the study was to determine the levels of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c14d8398-81e9-5200-aac7-1962d86b92d4
DOI: 10.21203/rs.3.rs-3760740/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Lipoprotein(a) is associated with higher DNA damage in patients with heterozygous familial hypercholesterolemiaDOI 10.21203/rs.3.rs-3760740/v1Read

Oxidative DNA Damage and Arterial Hypertension in Light of Current ESC GuidelinesSemantic proximity Read

Oxidative burden in familial hypercholesterolemiaSemantic proximity Read

Lipoprotein(a) levels in familial hypercholesterolemia: an important predictor of cardiovascular disease independent of the type of LDL receptor mutation.Semantic proximity Read

[Apolipoprotein(a) phenotypes as markers of genetic susceptibility for cardiovascular risk in occupational medicine].Semantic proximity Read

Do genetically determined very high and very low LDL levels contribute to Lp(a) plasma concentration?Semantic proximity Read

Role of Lipoprotein(a) Reduction in Cardiovascular DiseaseSemantic proximity Read

DNA damage and repair in atherosclerosisSemantic proximity Read

[Lipoprotein(a) is associated to atherosclerosis in primary hypercholesterolemia].Semantic proximity Read

Lipoprotein(a) in hereditary hypercholesterolemia: Influence of the genetic cause, defective gene and type of mutation.Semantic proximity Read

Age and metabolic risk factors associated with oxidatively damaged DNA in human peripheral blood mononuclear cellsSemantic proximity Read

DNA Damage and Repair in Atherosclerosis: Current Insights and Future PerspectivesSemantic proximity Read

Lipoprotein(a) levels in coronary heart disease-susceptible and -resistant patients with familial hypercholesterolemia.Semantic proximity Read