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Do genetically determined very high and very low LDL levels contribute to Lp(a) plasma concentration?

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Feb 2025

Giammanco Antonina, Noto Davide, Nardi Emilio, Gagliardo Carola Maria, Scrimali Chiara, Brucato Federica, Spina Rossella, Barbagallo Carlo Maria, Caldarella Rosalia, Ciaccio Marcello, Cefalù Angelo Baldassare, Averna Maurizio

Abstract excerpt

BACKGROUND AND AIMS: Lipoprotein(a) [Lp(a)] is a well-recognized risk factor for atherosclerotic cardiovascular disease (ASCVD). Few data are available on the distribution of Lp(a) levels among subjects at different cardiovascular risk and in subjects with monogenic and polygenic dyslipidemias (familial hypercholesterolemia, FH and familial hypobetalipoproteinemia type 1, FHBL1). The aim of this study was to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39271391
DOI: 10.1016/j.numecd.2024.08.016

Genes

FH
LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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