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Article

Oxidative burden in familial hypercholesterolemia

11 Jan 2018

Abstract excerpt

Familial hypercholesterolemia (FH) is a genetic disorder characterized by high serum levels of low-density lipoprotein cholesterol (LDL-c). FH is characterized by accelerated development of atherosclerosis and represents the most frequent hereditary cause of premature coronary heart disease. Mutations of the LDL receptor gene are the genetic signature of FH, resulting in abnormal levels of circulating LDLs....

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PMID: 29323716
DOI: 10.1002/jcp.26466

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