Article

Endothelial exosome plays functional role during rickettsial infection

2020-11-17

Abstract excerpt

Spotted fever group rickettsioses (SFRs) are devastating human infections. Vascular endothelial cells (ECs) are the primary targets of infection. Edema resulting from EC barrier dysfunction occurs in the brain and lungs in most cases of lethal SFR, but the underlying mechanisms remain unclear. The aim of the study is to explore the potential role of Rickettsia ( R )-infected, EC-derived exosomes (Exos) during in...

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Literature Corpus work: c144bd41-85ab-507b-9d09-28ba1d354f74
DOI: 10.1101/2020.11.16.385740

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