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Navigating the Maze of Mass Spectra: A Machine-Learning Guide to Identifying Diagnostic Ions in O-Glycan Analysis

2024-07-02

Abstract excerpt

Structural details of oligosaccharides, or glycans, often carry biological relevance, which is why they are typically elucidated using tandem mass spectrometry. Common approaches to distinguish isomers rely on diagnostic glycan fragments for annotating topologies or linkages. Diagnostic fragments are often only known informally among practitioners or stem from individual studies, with unclear validity or generaliz...

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Literature Corpus work
6f32d1a1-2818-54e5-858a-eb1dbde49c69
DOI
10.1101/2024.06.28.601175
Open publication

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Navigating the Maze of Mass Spectra: A Machine-Learning Guide to Identifying Diagnostic Ions in O-Glycan AnalysisDOI 10.1101/2024.06.28.601175
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