Liquid-liquid phase separation -related gene can predict prognosis and influence immune microenvironment in acute myeloid leukemia

Abstract excerpt

<title>Abstract</title> <p>Acute myeloid leukaemia (AML) is a hematopoietic malignant tumour, whose growth and metastasis have been found to be closely correlated with liquid-liquid phase separation (LLPS), however, the molecular mechanisms and immunological value of LLPS in AML has not been reported. Consequently, this study aims to develop a precise prognostic risk model predicated on LLPS-associated key genes...

Topics

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• Biomarkers, Tumor
• Gene Expression Profiling
• Leukemia, Myeloid, Acute
• Lymphangiogenesis
• Prognosis
• Sequence Analysis, RNA
• Single-Cell Analysis
• Single-Cell Gene Expression Analysis

Identifiers and source

Literature Corpus work

c07acf57-752a-5721-826b-327c91a43916

DOI

10.21203/rs.3.rs-3939061/v1