Article

Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection <i>in vitro</i> by hindering membrane fusion

2020-12-23

Abstract excerpt

An ongoing pandemic of coronavirus disease 2019 (COVID-19) is now the greatest threat to the global public health. Herbal medicines and their derived natural products have drawn much attention to treat COVID-19, but there has been no natural product showing inhibitory activity against SARS-CoV-2 infection with detailed mechanism. Here, we show that platycodin D (PD), a triterpenoid saponin abundant in Platycodon...

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Literature Corpus work: c03f6340-6c73-5a3d-9e4b-cf5b5fabeb87
DOI: 10.1101/2020.12.22.423909

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