Article

Circadian clock circuitry deconvolutes colorectal cancer and lung adenocarcinoma heterogeneity in a dynamic time-related framework

2022-12-19

Abstract excerpt

<title>Abstract</title> <p>Increasing evidence imputes cancer progression and resistance to therapy to intra-tumor molecular heterogeneity set off by cancer cell plasticity. Re-activation of developmental programs strictly linked to epithelial-to-mesenchymal transition and gaining of stem cells properties are crucial in this setting. Many biological processes involved in cancer onset and progression show rhythmic...

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Literature Corpus work: c027b7c5-0e84-5c84-a8fd-8ccdaed5983b
DOI: 10.21203/rs.3.rs-2297936/v1

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