Article

MAP3K1 Expression is Associated With Progression and Poor Prognosis of Hormone Receptor-Positive, HER2-Negative Early-Stage Breast Cancer

2020-08-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1) participates in the MAPK signal transduction pathway, responding to a number of mitogenic and metabolic stimuli, which may be related to breast cancer susceptibility and progression. In this study, we assessed whether overexpression of MAP3K1 promotes proliferation, migration, and invasion of breast cance...

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Literature Corpus work: bfa8f70a-8b1e-52e8-927a-48b68dfe1683
DOI: 10.21203/rs.3.rs-53956/v1

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