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Article

An Anaplastic Lymphoma Kinase Pathway Signature is associated with Cell De-differentiation, Neoadjuvant Response and Recurrence Risk in Breast Cancer

2019-08-29

Abstract excerpt

<title>Abstract</title> <p>The role of ALK signaling in the pathogenesis of breast cancer (BC) is not clear. Previously we generated a gene signature for ALK pathway based on the difference of gene expression profiles between tumor cells with activated and inactive ALK pathway. Here, this signature was used to compute ALK pathway activity in BC samples from 42 microarray datasets, and the associations between ALK...

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Literature Corpus work
bf9f7336-11ca-591c-b181-8b79ac9cce9c
DOI
10.21203/rs.2.12140/v1
Open publication

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An Anaplastic Lymphoma Kinase Pathway Signature is associated with Cell De-differentiation, Neoadjuvant Response and Recurrence Risk in Breast CancerDOI 10.21203/rs.2.12140/v1
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