Back to search

Article

Characterization and Anticonvulsant Effects of a Colombian Cannabis sativa Extract: A Preclinical Study in Murine Models of Epilepsy

2026-02-25

Abstract excerpt

<title>Abstract</title> <p>Background: Epilepsy represents one of the most prevalent chronic neurological disorders worldwide, affecting approximately 50 million people globally. Despite the availability of numerous antiseizure medications (ASMs), approximately 30% of patients develop drug-resistant epilepsy, necessitating the exploration of novel therapeutic alternatives. Cannabis sativa has emerged as a promisi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
bf978366-4d6f-599b-9b80-b62c3059aa30
DOI
10.21203/rs.3.rs-8935396/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Characterization and Anticonvulsant Effects of a Colombian Cannabis sativa Extract: A Preclinical Study in Murine Models of EpilepsyDOI 10.21203/rs.3.rs-8935396/v1
CBD can be combined with additional cannabinoids for optimal seizure reduction and requires GPR55 for its anticonvulsant effectsSemantic proximity
Cannabidiol in Neurology: Current Insights and Translational PerspectivesSemantic proximity
Potential clinical benefits of CBD-rich Cannabis extracts over purified CBD in treatment-resistant epilepsy: observational data meta-analysisSemantic proximity
WITHDRAWN: Astaxanthin improved carbamazepine efficacy and mood comorbidities in epileptic rats through GABAergic signaling pathway enhancementSemantic proximity
Animal models in EpilepsySemantic proximity
Colombian consensus of treatment with pure cannabidiol (CBD) in PsychiatrySemantic proximity
Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex.Semantic proximity
Modulating Neural Excitability in Epilepsy: A Systems-Level Perspective on Cannabinoid–Terpene SignalingSemantic proximity
Exploring the anti-convulsant potential of cordia dichotoma leaf extract to combat seizures in swiss albino miceSemantic proximity
Phytochemical investigation of anti-proliferative active fractions of Cannabis sativa leads to isolate a new Compound Canniprene A and other bioactive compounds through bioassay guided fractionation and HPLC assisted purificationSemantic proximity
Anti-Inflammatory and Antiviral Effects of Cannabinoids in Inhibiting and Preventing SARS-CoV-2 InfectionSemantic proximity
Neuroprotective potential of Cannabis sativa-based oils in Caenorhabditis elegansSemantic proximity
Select a neighboring publication to make it the new centre.