Article
Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex.
Epilepsia - 1 Oct 2016
Hess Evan J, Moody Kirsten A, Geffrey Alexandra L, Pollack Sarah F, Skirvin Lauren A, Bruno Patricia L, Paolini Jan L, Thiele Elizabeth A
Abstract excerpt
OBJECTIVE: Tuberous sclerosis complex (TSC) is an autosomal-dominant genetic disorder with highly variable expression. The most common neurologic manifestation of TSC is epilepsy, which affects approximately 85% of patients, 63% of whom develop treatment-resistant epilepsy. Herein, we evaluate the efficacy, safety, and tolerability of cannabidiol (CBD), a nonpsychoactive compound derived from the marijuana plant,...
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