Back to search

Article

LncRNA <i>OIP5-AS1</i> is overexpressed in undifferentiated oral tumors and integrated analysis identifies as a downstream effector of stemness-associated transcription factors

2018-03-19

Abstract excerpt

Long non-coding RNAs (lncRNAs) play an important role in the regulation of key cellular processes in early development and in cancer. LncRNA Oip5-as1 facilitates stem cell self-renewal in mouse by sponging mmu-miR-7 and modulating NANOG level, yet its role in cancer is less understood. We analyzed OIP5-AS1 expression in oral tumors and in TCGA datasets. We observed overexpression of OIP5-AS1 in oral tumors ( P...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
be57d0eb-75ee-50d7-b19c-823b93835fcf
DOI
10.1101/285270
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
LncRNA <i>OIP5-AS1</i> is overexpressed in undifferentiated oral tumors and integrated analysis identifies as a downstream effector of stemness-associated transcription factorsDOI 10.1101/285270
Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding QuestionsSemantic proximity
The role of long non-coding RNA FGD5-AS1 in cancerSemantic proximity
β-Catenin/POU5F1/SOX2 Transcription Factor Complex Mediates IGF-I Receptor Signaling and Predicts Poor Prognosis in Lung AdenocarcinomaSemantic proximity
Coexpression of <i>Oct4</i> and <i>Nanog</i> Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal TransdifferentiationSemantic proximity
Targeting cancer stem cells: emerging role of Nanog transcription factorSemantic proximity
Insights into the Nanog gene: A propeller for stemness in primitive stem cellsSemantic proximity
Functional Evidence that the Self-Renewal Gene <i>NANOG</i> Regulates Human Tumor DevelopmentSemantic proximity
LINC01234 regulates microRNA-27b-5p to induce the migration, invasion and self-renewal of ovarian cancer stem cells through targeting SIRT5Semantic proximity
NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cellsSemantic proximity
FXYD6 Functions as a Tumor Suppressor in Lung Adenocarcinoma via the OIP5-AS1/miR-4735-3p/FXYD6 AxisSemantic proximity
Long Non-coding RNAs: Key Regulators of Tumor Epithelial/Mesenchymal Plasticity and Cancer StemnessSemantic proximity
MSX2 represses tumor stem cell phenotypes within oral squamous cell carcinomas via SOX2 degradation.Semantic proximity
Select a neighboring publication to make it the new centre.