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Dengue virus infected patients can generate false positives in the ‘gold standard’<i>Leptospira</i>spp. microscopic agglutination test (MAT), immunofluorescence assays (IFAs), and immunoblot assays due to cross-reactive IgG and/or IgM antibodies against their outer surface membrane proteins

2023-03-16

Abstract excerpt

There are overlapping world distributions of the mosquito-borne dengue viruses (DENVs) and water-borne bacterial disease leptospirosis which cause large numbers of human infections and fatalities. As such, early differential diagnosis is required for appropriate early leptospirosis antibiotic therapy or DENV patient supportive care, but co-infections have also been reported. From 200 paired (S1 and S2) serum sampl...

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Literature Corpus work
bdd60162-d14a-592e-b7f6-1ed115e86122
DOI
10.1101/2023.03.13.23286524
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Dengue virus infected patients can generate false positives in the ‘gold standard’<i>Leptospira</i>spp. microscopic agglutination test (MAT), immunofluorescence assays (IFAs), and immunoblot assays due to cross-reactive IgG and/or IgM antibodies against their outer surface membrane proteinsDOI 10.1101/2023.03.13.23286524
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