Article

Navigating cross-reactivity and host species effects in a serological assay: A case study of the microscopic agglutination test for <i>Leptospira</i> serology

2024-03-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Serology (the detection of antibodies formed by the host against an infecting pathogen) is frequently used to assess current infections and past exposure to specific pathogens. However, the presence of cross-reactivity among host antibodies in serological data makes it challenging to interpret the patterns and draw reliable conclusions about the infecting pathogen or strain....

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Literature Corpus work: 5a26705a-acec-5f7a-a106-03f791395736
DOI: 10.1101/2024.03.05.583452

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