Back to search

Article

Optimization and clinical validation of new and improved TaqMan Real-Time PCR assays for the detection of pathogenic <i>Leptospira</i>

2026-08-17

Abstract excerpt

<h4>ABSTRACT</h4> Leptospirosis is an infectious neglected zoonotic disease caused by pathogenic bacteria of the genus Leptospira . The genus comprises 43 pathogenic species, divided into two clades (P1 and P2), with the potential to cause disease on animals and humans. Despite the major impact of this disease on animal and human health, few quantitative real-time polymerase chain reaction (qPCR) assays have bee...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
39b3b7db-104d-5e4e-a69f-d2d672bfe562
DOI
10.64898/2026.08.13.26359137
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Optimization and clinical validation of new and improved TaqMan Real-Time PCR assays for the detection of pathogenic <i>Leptospira</i>DOI 10.64898/2026.08.13.26359137
A Validated Multiplex Real-Time PCR Assay for the Diagnosis of Infectious Leptospira spp.: A Novel Assay for the Detection and Differentiation of Strains From Both Pathogenic Groups I and IISemantic proximity
Divergent lineages of pathogenic <i>Leptospira</i> species are widespread and persisting in the environment in Puerto Rico, USASemantic proximity
Leptospirosis-persistence of a Dilemma: An Overview with Particular Emphasis on Trends and Recent Advances in Vaccines and Vaccination StrategiesSemantic proximity
Next-Generation Sequencing Analysis of Pathogenic Leptospira: A Way Forward for Understanding Infectious Disease Dynamics in Low/Middle-Income, Disease-Endemic Settings.Semantic proximity
Diagnostic Accuracy of Real-Time PCR Assays Targeting 16S rRNA and lipl32 Genes for Human Leptospirosis in Thailand: A Case-Control StudySemantic proximity
First isolation and genotyping of pathogenic Leptospira spp. from Austria.Semantic proximity
Culture-Independent Detection and Identification of <i>Leptospira</i> SerovarsSemantic proximity
An Extended Multilocus Sequence Typing (MLST) Scheme for Rapid Direct Typing of Leptospira from Clinical SamplesSemantic proximity
Pathogenic <i>Leptospira</i> species identified in dogs and cats during neutering in ThailandSemantic proximity
Phylogenetic analysis of LipL32 gene sequence of different pathogenic serovars of Leptospira.Semantic proximity
Evolutionary insights into the emergence of virulent <i>Leptospira</i> spirochetesSemantic proximity
Sensitive Real-Time PCR Detection of Pathogenic Leptospira spp. and a Comparison of Nucleic Acid Amplification Methods for the Diagnosis of LeptospirosisSemantic proximity
Select a neighboring publication to make it the new centre.