Article

From Metabolism to Malignancy: Profiling Diabetes-Related Genes in Hepatocellular Carcinoma

2025-10-08

Abstract excerpt

Hepatocellular carcinoma (HCC) and diabetes mellitus both affect the liver, a key metabolic organ. This study uses bioinformatics to explore genetic links between Type 1 Diabetes (T1D) and HCC prognosis. Eleven HCC gene expression datasets from GEO and one TCGA-LIHC dataset were analyzed. Gene Set Enrichment Analysis (GSEA) identified up- and downregulated genes after data normalization in R. Four datasets (GSE640...

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Literature Corpus work: bdb7eafc-aa00-5d98-8cd3-c442a266de7a
DOI: 10.1101/2025.10.07.680510

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