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From genes to therapy: a lipid Metabolism-Related genetic risk model predicts HCC outcomes and enhances immunotherapy

19 May 2025

Abstract excerpt

BACKGROUND: Hepatocellular Carcinoma (HCC) is related to dysregulated lipid metabolism and immunosuppressive microenvironment. This study developed a genetic risk model using lipid metabolism-related genes to predict survival and immune patterns in HCC patients. METHODS: Differentially expressed genes (DEGs) related to lipid metabolism were identified in HCC via the TCGA-LIHC dataset. A risk model for survival...

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Share to Cancer, Lipids, and Metabolism
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40389832
DOI: 10.1186/s12885-025-14306-6

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