Article

BUB1 inhibition sensitizes lung cancer cell lines to radiotherapy and chemoradiotherapy

2024-04-23

Abstract excerpt

<h4>Background</h4> Lung cancer is a major public health concern, with high incidence and mortality. Despite advances in targeted therapy and immunotherapy, microtubule stabilizers (paclitaxel, docetaxel), DNA intercalating platinum drugs (cisplatin) and radiation therapy continue to play a critical role in the management of locally advanced and metastatic lung cancer. Novel molecular targets would provide opport...

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Literature Corpus work: bd85c4c3-6322-5137-958d-2893d124e6c3
DOI: 10.1101/2024.04.19.590355

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