Article

<i>Chlamydia trachomatis</i> infection upregulates MicroRNA21 to deplete tumor suppressor PTEN

2026-05-12

Abstract excerpt

Infection with obligate intracellular Chlamydia trachomatis (Ct) has been associated with cervical and ovarian carcinoma in humans. The possible cause of the tumor-promoting effect of the infection is thought to be a manipulation of host signaling pathways, which are essential for the growth of the bacteria, and which at the same time can support tumor growth. The PI3K and MAPK signaling cascades are outstanding...

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Literature Corpus work: bcc5c784-7a7f-574d-bd0e-9bb4652b8c7a
DOI: 10.64898/2026.05.11.723860

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