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MicroRNA-profiling of miR-371~373- and miR-302/367-clusters in Serum and Cerebrospinal Fluid Identify Patients with Intracranial Germ Cell Tumors

2021-11-10

Abstract excerpt

<title>Abstract</title> <p>Purpose: Intracranial germ cell tumors (iGCT) comprise germinoma and non-germinoma. Their diagnosis predominantly relies on biopsy as only one-fifth of patients present with elevated biomarkers (AFP/ß-HCG) in serum or cerebrospinal fluid (CSF). MicroRNAs (miR/miRNA) have emerged as non-invasive biomarkers in extracranial GCT and may potentially facilitate non-invasive diagnosis in iGCT....

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Literature Corpus work
bc6377db-4252-5379-bf96-e1956ac8f6cb
DOI
10.21203/rs.3.rs-1054745/v1
Open publication

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