Article

No evidence that plasmablasts transdifferentiate into developing neutrophils in severe COVID-19 disease

2020-09-28

Abstract excerpt

A recent study by Wilk et al. of the transcriptome of peripheral blood mononuclear cells (PBMCs) in seven patients hospitalized with COVID-19 described a population of “developing neutrophils” that were “phenotypically related by dimensionality reduction” to plasmablasts, and that these two cell populations represent a “linear continuum of cellular phenotype” 1 . The authors suggest that, in the setting of acute...

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Literature Corpus work: bc2903ec-7e46-5104-83aa-19947c5277b5
DOI: 10.1101/2020.09.27.312538

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