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<i>In silico</i> screening of TMPRSS2 SNPs that affect its binding with SARS-CoV2 spike protein and directly involved in the interaction affinity changes

2021-09-29

Abstract excerpt

In this paper, we used in silico analysis to shed light on the possible interaction between TMPRSS2 and SARS-CoV2 spike (S) protein by examining the role of TMPRSS2 single nucleotide polymorphisms (SNPs) in relation with susceptibility and inter-individual variability of SARS-CoV2 infection. First, we used molecular docking of human TMPRSS2 protein to predict the binding site of TMPRSS2, especially the TMPRSS2 lin...

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Identifiers and source

Literature Corpus work
bc1924b9-829a-5b91-8643-0c128a47bd04
DOI
10.1101/2021.09.29.462283
Open publication

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