Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular docking studies of Indian variants of pathophysiological proteins of SARS-CoV-2 with selected drug candidates.

Journal of genetics - 1 Jan 2021

Sridhar Shruti, Saha Gourav, Lata Sneha, Mehrotra Rajesh

Abstract excerpt

SARS-CoV-2 pandemic has recently made the entire world come to a standstill. The number of cases in the world, especially India, have been increasing exponentially. The need of the hour is to assimilate as much data as possible to fast track the pipeline of bringing in new therapeutic tools against this fatal virus. In this brief communication, we aim to throw light on the various variants of the proteins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to COVID-19 Drug Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Discovery

Share to Endoplasmic Reticulum Chaperone BiP

Share to Molecular Docking Simulation

Share to Pandemics

Share to Serine Endopeptidases

Share to Spike Glycoprotein, Coronavirus

Source

Open in PubMed Open full text

Identifiers

PMID: 34553696
PMCID: PMC8435403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular docking studies of Indian variants of pathophysiological proteins of SARS-CoV-2 with selected drug candidates.PMID 34553696Read ↗

Elucidating the role of N440K mutation in SARS-CoV-2 spike - ACE-2 binding affinity and COVID-19 severity by virtual screening, molecular docking and dynamics approach.Semantic proximity Read ↗

Mutational Stability Profiling and Functional Analysis of Spike Protein in Indian Sars Cov-2 Delta Variants: an in Silico AnalysisSemantic proximity Read ↗

Investigation of nonsynonymous mutations in the spike protein of SARS-CoV-2 and its interaction with the ACE2 receptor by molecular docking and MM/GBSA approach.Semantic proximity Read ↗

Emergence of RBD and D614G Mutations in Spike Protein: An Insight from Indian SARS-CoV-2 Genome AnalysisSemantic proximity Read ↗

Comparative Study of the Mutations Observed in the SARS-CoV-2 RBD Variants of Concern and Their Impact on the Interaction with the ACE2 Protein.Semantic proximity Read ↗

Pan-India novel coronavirus SARS-CoV-2 genomics and global diversity analysis in spike proteinSemantic proximity Read ↗

Impact of the Double Mutants on Spike Protein of SARS-CoV-2 B.1.617 Lineage on the Human ACE2 Receptor Binding: A Structural Insight.Semantic proximity Read ↗

Computational prediction of binding affinity and structural impact of three Pakistani SARS-CoV-2 spike RBD variants on human ACE2 interaction.Semantic proximity Read ↗

Computational analysis of affinity dynamics between the variants of SARS-CoV-2 spike protein (RBD) and human ACE-2 receptor.Semantic proximity Read ↗

Understanding the molecular interaction of SARS-CoV-2 spike mutants with ACE2 (angiotensin converting enzyme 2).Semantic proximity Read ↗

Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein.Semantic proximity Read ↗

Sequence analysis of Indian SARS-CoV-2 isolates shows a stronger interaction of mutated receptor binding domain with ACE2 receptorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.