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Refractory B-Cell-Acute Lymphoblastic Leukemia with 5q Deletion in remission with Tyrosine Kinase Inhibitor: A Case Report and Literature Review

2024-08-24

Abstract excerpt

Recently, PDGFRB rearrangements located on chromosome 5q have been documented in Philadelphia chromosome-like (Ph-like) B-progenitor acute lymphoblastic leukemia (B-ALL). Five genes were reported to be fused with PDGFRB in Ph-like ALL. Only the transcripts EBF1 and ATF7IP, have already been reported as regions targetable by tyrosine kinase inhibitor (TKI). The EBF1-PDGFRB gene fusion is rare, in B-ALL cases, and i...

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Literature Corpus work
bc11270f-7975-5468-98d6-495f6bda9f9f
DOI
10.22541/au.172451121.17441594/v1
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Refractory B-Cell-Acute Lymphoblastic Leukemia with 5q Deletion in remission with Tyrosine Kinase Inhibitor: A Case Report and Literature ReviewDOI 10.22541/au.172451121.17441594/v1
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