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Article

ATF 7 IP as a novel PDGFRB fusion partner in acute lymphoblastic leukaemia in children

15 Mar 2014

Abstract excerpt

We identified ATF7IP as a novel PDGFRB fusion partner in B-progenitor acute lymphoblastic leukaemia (B-ALL) and showed that B-ALL with ATF7IP/PDGFRB translocation is included within the genomic lesions of a Philadelphia chromosome (Ph)-like ALL subgroup. Comprehensive analyses of previous repositories of gene expression data sets disclosed that B-ALL cases with high PDGFRB expression level in the context of the...

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PMID: 24628626
DOI: 10.1111/bjh.12834

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