Article

Peptidases: promising antifungal targets of the human fungal pathogen, Cryptococcus neoformans

2022-01-01

Abstract excerpt

Cryptococcus neoformans is a globally important fungal pathogen, primarily inflicting disease on immunocompromised individuals. The widespread use of antifungal agents in medicine and agriculture supports the development of antifungal resistance through evolution, and the emergence of new strains with intrinsic resistance drives the need for new therapeutics. For C. neoformans, the production of virulence factors,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bb6c32d3-3a3d-5d9e-a572-84d37f993483
DOI: 10.1139/facets-2021-0157

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Peptidases: promising antifungal targets of the human fungal pathogen, Cryptococcus neoformansDOI 10.1139/facets-2021-0157Read

More than Just Protein Degradation: The Regulatory Roles and Moonlighting Functions of Extracellular Proteases Produced by Fungi Pathogenic for HumansSemantic proximity Read

Proteomics of Cryptococcus neoformans: From the Lab to the ClinicSemantic proximity Read

Identification of a fungal antibacterial endopeptidase that modulates immune responsesSemantic proximity Read

Virulence Factors as Targets for Anticryptococcal TherapySemantic proximity Read

The structure-function analysis of the Mpr1 metalloprotease determinants of activity during migration of fungal cells across the blood-brain barrier.Semantic proximity Read

Global proteomic analysis of <i>Cryptococcus neoformans</i> clinical strains reveals significant differences between latent and lethal infectionSemantic proximity Read

The emerging fungal pathogen Cryptococcus gattii: Epidemiology, pathogenesis, immunomodulatory attributes, and drug susceptibilitySemantic proximity Read

The molecular mechanism by which novel antibacterial peptides inhibit Cryptococcus neoformansSemantic proximity Read

Cryptococcus neoformans: historical curiosity to modern pathogenSemantic proximity Read

Glycosyltransferases and their products: cryptococcal variations on fungal themesSemantic proximity Read

Revealing the dynamics of fungal disease with proteomicsSemantic proximity Read

Associations between Cryptococcus Genotypes, Phenotypes, and Clinical Parameters of Human Disease: A ReviewSemantic proximity Read