The molecular mechanism by which novel antibacterial peptides inhibit Cryptococcus neoformans

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Cryptococcosis, caused by <italic>Cryptococcus neoformans</italic> , is a major global public health concern. The infection primarily begins in the lungs. Cryptococcosis is characterized by significant consequences and low cure rates in immunocompromised individuals. Pulmonary cryptococcosis has become more common in recent years. Amphotericin B (AmB) and fl...

Topics

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• Antifungal resistance and susceptibility
• Antimicrobial Peptides and Activities
• Biochemical and Structural Characterization
• Fungal Infections and Studies
• Microbial Natural Products and Biosynthesis
• Peptidase Inhibition and Analysis
• Toxin Mechanisms and Immunotoxins

Identifiers and source

Literature Corpus work

c5978ca9-7f40-5a1d-9faa-22b86d4c8b6c

DOI

10.21203/rs.3.rs-8150680/v1