Article

Reproducibility of the radiosensitivity index and failure of CT radiomics as its surrogate: a public-data study in non-small cell lung cancer

2026-07-22

Abstract excerpt

<h4>Purpose</h4> The radiosensitivity index (RSI) and genomic-adjusted radiation dose (GARD) are increasingly treated as quantitative inputs to radiotherapy dose calculation. Two reproducibility issues bear on this use: whether CT radiomics can non-invasively recover RSI, and whether one coefficient of the equation is uniquely specified (printed CDK1 but implemented as PAK2). We examine both on public data. <h4>M...

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Literature Corpus work: ba99daac-3814-54cd-bf59-33bb9485d754
DOI: 10.64898/2026.07.20.26358526

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