Article

ETV6-NTRK3 is Associated With Trisomy 8 and Sensitive to TRK Inhibitor in Hematologic Malignancy: Case Report of a Refractory AML and Review of the Literature

2021-01-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The <italic>ETV6-NTRK3</italic> fusion transcript has been found to recurrently identified in both solid tumors and leukemias. It has attracted a lot of interest for the clinical targeted therapy and genetic features in <italic>ETV6-NTRK3</italic> positive solid tumors. While the t(12;15)(p13;q25)/<italic>ETV6-NTRK3</italic> is a rare genetic aberration in hemat...

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Literature Corpus work: ba2064c9-bfdf-50b2-a090-fcd620cbbe00
DOI: 10.21203/rs.3.rs-143398/v1

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