Scalable image-based visualization and alignment of spatial transcriptomics datasets

Abstract excerpt

We present STIM, an imaging-based computational framework focused on visualizing and aligning high-throughput spatial sequencing datasets. STIM is built on the powerful, scalable ImgLib2 and BigDataViewer (BDV) image data frameworks and thus enables novel development or transfer of existing computer vision techniques to the sequencing domain characterized by datasets with irregular measurement-spacing and arbitrar...

Topics

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• Brain
• Computer Simulation
• Gene Expression Profiling
• Oligonucleotide Array Sequence Analysis
• Phenotype
• Polymorphism, Single Nucleotide
• Technology
• Transcriptome

Identifiers and source

Literature Corpus work

b9e4f200-bb62-58c3-b332-3bd36265f126

DOI

10.1101/2021.12.07.471629