Article

Stage Ⅳb Pulmonary Sarcomatoid Carcinoma with EGFR L861Q KRAS Co-mutation and High PD-L1 Expression Neoadjuvant Immunochemotherapy Combined with Surgery Achieves Near MPR

2026-01-30

Abstract excerpt

<title>Abstract</title> <p> <bold>Background Pulmonary sarcomatoid carcinoma (PSC) is a rare, highly aggressive non-small cell lung cancer (NSCLC) subtype (0.1%–4% of lung malignancies)</bold> <sup> <bold>[3]</bold> </sup> <bold>. Clinically, it mainly affects smokers, with half diagnosed at advanced stages; pathologically, it is defined by cytokeratin-vimentin co-expression. Molecularly, classical EGFR-sens...

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Literature Corpus work: b90a362b-4718-5d6a-807c-fb3157dd8fd3
DOI: 10.21203/rs.3.rs-8460147/v1

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