Article
Inter-relationship between PD-L1 expression and clinic-pathological features and driver gene mutations in pulmonary sarcomatoid carcinomas.
Lung cancer (Amsterdam, Netherlands) - 1 Nov 2017
Lococo Filippo, Torricelli Federica, Rossi Giulio, Alifano Marco, Damotte Diane, Rapicetta Cristian, Tamagnini Ione, Cavazza Alberto, Piana Simonetta, Galeone Carla, Paci Massimiliano, Ciarrocchi Alessia
Abstract excerpt
INTRODUCTION: Pulmonary Sarcomatoid Carcinoma (PSC) is a rare subset of NSCLC, associated with worse prognosis and resistant to platinum-based regimens. Recent investigations have shown high levels of PD-L1 expression in PSC, providing a rationale for the potential use of immunotherapy. In this study, we investigated whether the PD-L1 expression was related to clinico-pathologic and molecular characteristics....
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