Article

Glycerol-Driven Contamination in PCR Labs: Implications for Diagnostic Accuracy and Laboratory Safety

2025-12-09

Abstract excerpt

<h4>Background</h4> A key component of diagnostics in low- and middle-income (LMIC) nations is polymerase chain reaction (PCR). Despite its high sensitivity, PCR is vulnerable to laboratory contamination, particularly from aerosolized DNA. Glycerol, a common additive that enhances enzyme activity, may also promote aerosol generation—an issue not yet thoroughly investigated. <h4>Objective</h4> To determine whethe...

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Literature Corpus work: b8d0ea23-d2b2-51ec-b748-ac0024978402
DOI: 10.64898/2025.12.08.25341814

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